Epileptic Network Manipulation

Vacancy Reference Number
Closing Date
9 Jul 2021
£36,028 - £43,533 per annum
UCL Queen Square Institute of Neurology London WC1N 3BG United Kingdom
36 months in the first instance
The post holder will use viral delivery of molecular tools to manipulate the excitability of discrete brain regions involved in seizure initiation and propagation. The project is central to an MRC-funded programme of research aimed at optimizing gene therapy for refractory epilepsy, with a view to clinical translation. It will be supervised by DM Kullmann, MC Walker, S Schorge (UCL Department of Neuroscience, Physiology and Pharmacology) and G Lignani. Applicants should have a PhD (or be close to obtaining) or equivalent in Neuroscience or a related discipline. Experience of in vitro or in vivo electrophysiology, stereotaxic surgery and electrode implantation is essential, as is experience of working with rodents, colony maintenance and surgery. IT proficiency at advanced user level (electrophysiological and imaging data processing, statistical analysis programs), good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting and strong problem-solving abilities are also required. A Personal Licence from the UK Home Office to work with rodents and experience of immunofluorescence and confocal microscopy are desirable.

Further Information

www.ucl.ac.uk/hr/jobs Reference: 1876706 or https://t.co/hqwnlVxn0P

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