Post-Doctoral Cell Biologist

Closing Date

28 Jun 2017

Address

AstraZeneca UK Limited Cambridge, UK

Duration

1 year initially

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.
As a highly motivated Post-DoctoralCell Biologist you will join the growing Neuroscience IMED (Innovative Medicines and Early Development) research group in Cambridge, UK where you will conduct experiments to help explore novel mechanisms and pathways involved in neurological disorders including neurodegeneration and pain. This is a 12 month Fixed Term Contract (FTC) initially, although there could be scope to extend dependant on business needs.
The Neuroscience IMED manages AstraZeneca’s entire portfolio of CNS and pain programs from target identification through Phase II proof of concept studies. The IMED is built around a bold collaborative approach that brings together the great science of the biotech and academic worlds with the scientific and commercial reach of AstraZeneca, one of the world’s largest global biopharmaceutical companies. 
 

Main Duties and Responsibilities

Working independently as well as part of a team you will design, execute and optimise biological assays using primary cells to support both basic research as well as pipeline projects as required.

Essential Requirements

• Newly qualified PhD in a life science
• Strong hands-on experience with primary cell culture, with experience of isolating primary neurons/astrocytes/microglia from tissue
• Ability to evaluate cellular responses by various means, for example neurite outgrowth/synapse loss, multi-colour flow cytometry, ELISA, western blotting and/or other similar technologies
• Highly organized and self-motivated, with the ability to work well as part of a team
• Uses significant technical discretion to influence the design, planning and execution of experiments, interpretation of the data and optimisation of assays
• A background knowledge of neuroscience, preferably in the neurodegeneration or pain areas
• Strong verbal and written communication skills

Desirable Requirements

Experience with 1 or more of the following areas would be advantageous but is not a requirement:

• Industry or academic working experience
• Hands-on experience with primary cell co-culture systems eg neuron-microglia
• Familiar with molecular biology techniques (cloning, viral vectors, RT-PCR etc) and transcriptomics
• Experience with immunohistochemistry on CNS tissues
• Competency with imaging methods such as live cell confocal microscopy

More information can be found here

Further Information

https://uk.euspert.com/joboffers/post-doctoral-cell-biologist-neuroscience-1421987.html?utm_source=Indeed&utm_medium=cpc&utm_campaign=Indeed