Postdoc: chemogenetic tools

Vacancy Reference Number
Closing Date
1 Dec 2021
£36,770 - £42,048
UCL Queen Square Institute of Neurology
30 months in the first instance

Applications are invited for a Research Fellow in the Department of Clinical and Experimental Epilepsy. The post holder will design, optimize and validate molecular tools to manipulate the excitability of neurons and brain circuits. The project will advance fundamental neuroscience and the treatment of neurological and psychiatric disorders. It will feed into a programme of research into gene therapy for refractory epilepsy, with a view to clinical translation. It will be supervised by Professor Dimitri M Kullmann. The post is available immediately and is funded by a grant from the Medical Research Council for 30 months in the first instance Applicants should have (or be close to obtaining) a PhD or equivalent in molecular or cellular neuroscience or a related discipline. Experience of molecular pharmacology, medicinal chemistry, molecular modelling, and/or cellular electrophysiology is essential, as is a deep understanding of G-protein coupled receptor signalling. Expertise in cell-based arrays, immunofluorescence and confocal microscopy, IT proficiency at advanced user level, excellent oral and written communication skills, good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting, and strong problem-solving abilities are also required. Experience of working with viral vectors is desirable. Appointment at Grade 7 (salary £36,770 - £42,048 per annum) is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £32,217 - £33,958 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date in post.

Further Information

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Contact Details

Dimitri Kullmann