Postdoctoral Research Associate ALS - University of Edinburgh

Vacancy Reference Number
Closing Date
5 Jul 2019
£33,199 to £36,261 per annum
Quantitative Biology, Biochemistry & Biotechnology, University of Edinburgh
Fixed term for 3 years

College of Science and Engineering

A highly motivated candidate is invited to join the research group of Dr Christopher Sibley as a post-doctoral researcher. The group studies molecular and cellular events underlying the neurodegenerative disease of amyotrophic lateral sclerosis (ALS). In this project, funded by the Royal Society and Wellcome Trust, the post-holder will identify the RNA metabolism changes that contribute to ALS aetiology at cell-type resolution. Specifically, the 3-year post will involve application of single-cell RNA sequencing and iCLIP to clinically relevant human tissue and induced pluripotent stem cell models of ALS alongside cell-based functional validations.

Applicants should have (or be near completion of) a PhD in neuroscience, medical sciences, biochemistry, genetics or another closely related field. Knowledge of RNA metabolism, molecular neuroscience and/or ALS is desirable, as is experience in a subset of the following techniques: single cell transcriptomics, RNA sequencing, CLIP (or related functional genomics approaches), induced pluripotent stem cell modelling, standard molecular biology techniques. The candidate should have an outstanding academic track record commensurate with their career stage and experience that includes peer-reviewed published work. She/he is expected to be active in developing and the project, to collaborate as appropriate, and to contribute to an enthusiastic working atmosphere. The candidate will benefit from training in a vibrant intellectual and collaborative environment.

More details of the lab’s work can be found at

The position is fixed-term, for 3 years. Starting salary: £33,199 - £36,261 per annum.

Closing date is 5 July 2019 at 5pm GMT.

Informal enquiries can be made to Dr. Christopher Sibley (

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336.

For more information and to apply, click here

Contact Details

Dr. Christopher Sibley: