We are seeking a highly motivated Postdoctoral Research Associate to join the Department of Basic and Clinical Neuroscience at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. The post is funded by the Alzheimer’s Society for three years. We have developed a new mouse model that we are using to investigate molecular mechanisms underlying the development of neurodegenerative diseases, such as Alzheimer’s disease and related disorders (Bondulich et al. 2016, PMID: 27297240). In particular, we are examining the influence of tau on disease mechanisms and cognitive processes (Guo et al. 2019, PMID: 30606258).
The aim of this project is to understand the molecular mechanisms underlying the detrimental effects of this disease-associated tau fragment on lysosomes and at synapses using cell and animal models. Experience in working with transgenic mouse models and primary neurons using advanced microscopy, biochemical, cell and molecular biology approaches would be advantageous. A good knowledge of defective signaling processes in dementia and related disorders is also required for this post. The successful applicants will join established research groups headed by Professor Diane Hanger: http://bit.ly/1NS5kAE and Dr Wendy Noble: https://tinyurl.com/y3qgry7p
This post will be offered on a fixed-term contract for 3 years.
This is a full-time post - 100% full time equivalent
The selection process will include a panel interview and a presentation.
Contact: Professor Diane Hanger: diane.hanger@kcl.ac.uk
To apply, please register with the King’s College London application portal and complete your application online.
For more information and to apply, click here
Professor Diane Hanger: diane.hanger@kcl.ac.uk
