Postdoctoral Research Scientist in Neuroscience

Vacancy Reference Number
146049
Closing Date
18 Jun 2020
Salary
£32,817 - £40,322 p.a
Address
Department of Physiology, Anatomy & Genetics, Centre for Neural Circuits and Behaviour, Tinsley Building, Mansfield Road, Oxford
Duration
fixed-term for 12 months

An opportunity has arisen for a Postdoctoral Research Scientist to join the laboratory of Professor Scott Waddell at the Centre for Neural Circuits and Behaviour at the University of Oxford.

The project will investigate the neural and molecular mechanisms of consolidated long-term memory, using Drosophila melanogaster as a model. The lab has recently developed and applied single-cell transcriptomic analyses to the study of memory. This cutting-edge cell-specific approach has unique potential to uncover cell-signalling processes that accompany the time line of memory consolidation.

The successful candidate will generate and use single-cell data to study these processes. They will then determine the importance of transcriptional changes of specific genes in memory-relevant mushroom body Kenyon Cells, dopaminergic neurons and mushroom body output neurons. The candidate will be expected to apply a multi-disciplinary approach to this ambitious research problem. They will be required to design and use a variety of behavioural assays, advanced loss and gain of function fly genetics, single-cell transcriptomics, apply optogenetic and thermogenetic neuronal manipulations, and perform in vivo and ex vivo functional imaging of relevant cells in the fly brain. They must actively participate and be involved with all aspects of the Waddell Lab, manage their own day to day academics duties and take responsibility for planning experiments which should be carried out in a timely fashion and to deadlines, represent the Waddell lab at national and international meetings, maintain drosophila stocks and supervise graduate and undergraduate student projects. Some adhoc teaching may be required.

The successful candidate will have a PhD or be near to completing a PhD in biological sciences with a specialisation in neuroscience, extensive research experience in drosophila neurobiology, experience of advanced fly genetics, and familiarity with neural circuit based analysis of memory in Drosophila and experience with behavioural experimentation, such as olfactory/visual memory. They will be able to quickly adapt to a new environment and be keen to learn new techniques as well as having excellent communications skills.

The post holder will be based at the Centre for Neural Circuits and Behaviour, Tinsley Building, Mansfield Road, Oxford, OX1 3TA. This is a full-time post, fixed-term for 12 months.

For more information and to apply, please click here.

Further Information

The closing date for applications is 12.00 noon on Thursday 18 June 2020.

Contact Details

Fiona Woods: fiona.woods@cncb.ox.ac.uk