Postdoctoral Researcher in Neurobiology - John Radcliffe Hospital, Oxford

Vacancy Reference Number
Closing Date
16 Sep 2019
£32,236 - £39,609 p.a
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford
3 years

An exciting opportunity has recently become available for a talented, hard-working Electrophysiologist and Cell Biologist, at the level of Postdoctoral Research Associate. The role will involve working on the molecular mechanisms of neurological disorders and development of new therapies. The initial focus of work will be on the role of the mTOR pathway in neurons and how this affects glutamatergic signalling in disease. This builds upon significant work conducted over the last three years, currently in preparation as a manuscript; as well as insights from collaborators in preclinical models.

The successful candidate will be required to link molecular perturbations that have been identified with neuronal functional consequences using patch-clamp recording, calcium imaging and multi-electrode arrays in stem cell models. Opportunities to learn stem cell disease model development will be provided. The candidate will be expected to provide support and guidance to other members of the team, including students where appropriate. Opportunities to develop novel disease models as well as develop new methods to understand nervous tissue function in health and disease will also be available.

The successful candidate will hold, or be working towards the completion of, a PhD/DPhil in molecular or cellular biology or neuroscience with evidence of strong training in patch clamp electrophysiology. Evidence of molecular biology techniques and skilled tissue culturing are essential. Excellent interpersonal skills, communication and organisational skills are essential, as is the ability to work independently and within a team. Training and experience of developing stem cell disease models and calcium imaging or multi-electrode arrays will prove beneficial.

The post is full-time for a fixed-term of 3 years in the first instance.

Only applications received before 12.00 midday on 16 September 2019 will be considered. Interviews will be held on 25 September 2019.

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