Research Assistant in Cellular Neuroscience

Vacancy Reference Number

144479

Closing Date

10 Jan 2020

Salary

£29,176 to £34,804 p.a. (Grade 6)

Address

Oxford

Duration

Funded for 1 year

Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, South Parks Road, Oxford

Targeting disease phenotypes in Parkinson’s patient iPSC-derived dopamine neurons.

Applications are invited for a Research Assistant in Cellular Neuroscience to work at the Laboratory of Molecular Neurodegeneration at the Oxford Parkinson's Disease Centre (OPDC) to support studies of disease mechanisms and target discovery in induced pluripotent stem cell (iPSC)-derived neuronal models of Parkinson’s disease (PD). 

This is an exciting opportunity to contribute to the development of novel therapeutic drug and target discovery for Parkinson’s. The postholder will work on target and drug discovery using human iPSC lines from Parkinson’s patients differentiated into dopamine neurons to investigate disease mechanisms and test therapeutic approaches. The project will be performed in collaboration with GSK and offers an exciting collaboration to work at the translational interphase of academic and industry drug discovery. 

Duties will include analysis of cell biology and drug responses in iPSC-derived neurons from Parkinson’s patients, and other cell models; interpretation of data; design and implementation of experiments; and preparation of data for publication. You will have excellent practical experience of working with neuronal cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is also essential. Applicants must have a PhD or equivalent in a biological subject and have experience in cellular neuroscience, cell biology or biochemistry.

The post is funded for 1 year and is available to start as soon as possible. The post will be based in the Laboratory of Molecular Neurodegeneration, Le Gros Clark Building, South Parks Road, Oxford OX1 3QX.

The closing date for applications is 12.00 midday on Friday 10 January 2020. Interviews are likely to be held week commencing 20 January 2020.

For more information and to apply, please click here. 

Contact Details

Informal enquiries may be directed Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk)