Research Fellow (UCL): Bioinformatics; identifying the underlying mechanisms of ALS

Vacancy Reference Number
Closing Date
24 Nov 2019
£35,965 - £43,470 per annum
Funded until 30 September 2021 in the first instance

Duties and Responsibilities

The Department of Neuromuscular Diseases is a hub for clinical and research excellence across the spectrum of spinal cord and neuromuscular diseases. Applications are invited for a Research Fellow to work on identifying the underlying mechanisms of ALS (Amyotrophic lateral sclerosis), a rapidly progressive, incurable and fatal disease that causes the degeneration of motor neurons (MNs) and consequent generalized paralysis. 

The successful applicant will work at the interface between a computational group, based at the UCL Genetics Institute (under the supervision of Dr Maria Secrier) and wet labs based at the UCL Queen Square Institute of Neurology (Dr Pietro Fratta, Professor Adrian Isaacs), with the opportunity to balance the time spent in both locations depending on the needs and preferences of the candidate.

The post is available immediately and is funded by a grant from the ERC until 30 September 2021 in the first instance.

Key Requirements

Applicants must have a PhD in Neuroscience, Biostatistics, Mathematics, Physics or related discipline, experience with scientific programming (R, Python and MATLAB) and computational biology, ideally high throughput sequence data analysis. The ability to work in a diverse group including computational and experimental neurobiologists, to write clearly and succinctly for publication, to prioritise own work for deadline and to present research findings with authority and coherence are also requirements. Experience in neuroscience and advanced statistics is desirable. 

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £31,479 - £33,194 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date.

For more information and to apply, please click here. 

Contact Details

If you have any queries regarding the application process, please contact Oksana Shapoval, HR Officer, UCL Queen Square Institute of Neurology, 23 Queen Square, London, WC1N 3BG (email: