Senior Histology Manager UK Dementia Research Institute-UCL

Vacancy Reference Number
Closing Date
16 Mar 2021
£44,737 - £52,764 per annum
UK DRI at UCL, Queen Square
Up to March 2023

Job Details

Dementia is the biggest health challenge of our century. To date, there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.

The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.

UCL’s strength in combining excellent clinical and basic neuroscience research to advance our understanding of neurodegeneration and identify novel targets and therapeutic approaches for dementia resulted in its selection as the hub of the UK DRI. Research at the?UK DRI at UCL?covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test. The groups believe in intervening earlier in disease in order to change the trajectory.

The Senior Histology Manager will be responsible for the technical, scientific and governance management of the UK DRI at UCL Histology Facility.

Key to the role will be working collaboratively with researchers (Group Leaders and Early Career) to support high-quality research using a range of histological methods on both preclinical and post-mortem human samples. The post-holder will offer technical support (infrastructure maintenance, technical training, and experimental design) and ensure Human Tissue Act and Health and Safety compliance at the Histology Facility.

Person Criteria

Applicants should have a PhD in Neuroscience or related discipline and demonstrable experience of supervision and training of students and/or technicians in histological methods. Extensive experience in a range of histological methods (tissue processing, tissue embedding, sectioning), staining (manual and automated) and data acquisition (to include slide scanner) is essential, as is experience of the maintenance of histology equipment (tissue processor, embedder, microtome, cryostat, vibratome and staining equipment).

Experience of managing pipeline workflows at a histological facility including sample management and of managing health and safety compliance is also a requirement. Experience of working with human tissues for histological studies, of in situ hybridisation and/or RNAScope or BASEScope, of histological study of preclinical models of dementia causing diseases, and knowledge of neuro-anatomy are desirable.

How to Apply

Contact Details

For informal enquiries contact Frances Wiseman (