Stem cells and cancer: the good, the bad and the ugly

External Event - 9th Dec 2019

Date And Time

Mon, 9 December 2019

17:30 – 18:30 GMT

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Shirley Hall

Chancellor's Building


EH16 4SB

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Inaugural lecture of Professor Steve Pollard

Professor of Stem Cell and Cancer Biology

During the normal development of our nervous system, neural stem cells are responsible for generating the large numbers of different neurons and glia that make up the adult brain. To do this, they deploy ‘master regulatory’ transcription factors, that switch on the appropraite genes at the right time and place. In human brain tumours, such as glioblastoma, these transcription factors are ‘highjacked’ and are activated inappropriately. This leads to uncontrolled proliferation of the cancer cells, and limits their ability to become specialised, mature cells. They become locked in a perpetual immature state.

In his inaugural lecture Steve Pollard will discuss the relevance of understanding normal brain development to our understanding of brain cancer. How do these cells become corrupted in glioblastoma? What mechanisms sustain their growth? How can we use this new knowledge to develop new therapies against these incurable cancers?

This lecture is free and open to all.

This lecture will be followed by a reception in the Sophia Jex Blake suite.


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