Transgenerational Regulation of Behaviour and Metabolism

External Event - 27th Oct 2020

Online event

Date - Tuesday 27 October, 14:00 – 15:00 GMT


The causes of obesity are multifactorial; a complex interaction between genetic and environmental factors. Epidemiological studies have revealed associations between maternal obesity and the increased susceptibility to develop obesity in progeny later in life.

Gitalee Sarkar (University of Oxford, UK) sets out to explore the specific link in animal models of obesity characterising the behavioural, neurochemical and metabolic phenotypes associated with metal high-fat diet at different stages of pre and postnatal development.

Soyoung Park (University of Southern California, USA) demonstrates that obesity is associated with the activation of endoplasmic reticulum stress and that neonatal treatment of obese mice with an ER-stress relieving drug causes long-term attenuation of body weight gain, in addition to food intake, glucose homeostasis and POMC projections. 

This is part of the ‘Physiology of Obesity: From Mechanisms to Medicine’ series.

Note: Registration closes at 23:59 on Monday 26 October 2020.

To register, click here

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