Training
Mice are one of the most widely used vertebrate models in neuroscience research and for translational drug discovery. Here, we will consider the advantages offered by the mouse in these contexts, along with some of the challenges in their experimental use. We will also consider some of the unanswered questions that remain. Recent research, using mouse models in the context of translational drug discovery for neurodevelopmental disorders, will be used to highlight some key benefits of conducting neuroscience research in mouse models. Attendees will walk away with a greater appreciation of the utility of the mouse models in neuroscience research, and a framework to facilitate critical consideration of the use of these models for effective translation. The talk also aims to stimulate conversations around future approaches in the use of mice for neuroscience research, how findings are complemented by approaches in other model systems, and the challenges future research leaders need to address to ensure optimal use of mice in translational neuroscience research.