Speakers
Afternoon Session
Dysfunction of the cerebellum is increasingly recognised as a contributor to schizophrenia. In a subchronic phencyclidine mouse model, we observed persistent impairments in balance and fine motor coordination, downregulation of Kv2.1 in cerebellar Purkinje and granule cells, and cytoarchitectural alterations. This work lays the foundation for further investigation of cerebellar molecular and cellular mechanisms underlying schizophrenia.