In vivo cellular and systems neuroscience position--dementia and cognition

Vacancy Reference Number
4678
Closing Date
13 Dec 2022
Salary
£35,333pa - £42,155pa
Address
UK Dementia Research Institute at the University of Edinburgh Chancellor's Building 49 Little France Crescent Edinburgh, EH16 4SB
Duration
2 years with extension possibility to 5 years
Applications are invited for a postdoctoral fellow position in Dr. Jian Gan’s lab in the UK Dementia Research Institute, Centre for Discovery Brain Sciences, at the University of Edinburgh. Our lab investigates real-time neurocircuit dynamics underlying network oscillations, cognition, and decision-making in vivo. With such knowledge, we sort to elaborate on what, where, when, and how such dynamism goes wrong in disease conditions, e.g. dementia. We approach these questions by a combination of state-of-the-art methodologies in neuroscience, for instance in vivo patch-clamp recording, large-scale silicon probe recording, well-controlled quantitative behaviors in virtual reality, and optogenetics. Successful candidates will have a PhD in neuroscience, physiology, pharmacology, psychology or related quantitative disciplines (e.g. computer science, engineering, mathematics, and physics) with a strong curiosity in neural circuits and animal models of neural diseases. Experience in electrophysiology or Ca2+ imaging, stereotaxic surgery, behavioral training, and histology is highly desirable. We particularly encourage candidates who are with in vitro patch-clamp recording experience and interested in learning in vivo patch-clamp to apply. We are also keen to seek candidates who have in vivo electrophysiology or Ca2+ imaging experience and interested in learning quantitative analysis of cognitive behaviour. Some proficiency in relevant programming languages (e.g. MATLAB, C++, Python, R) with regard to analyzing electrophysiological/imaging data or signal processing of neural networks is advantageous. The projects will be in close collaboration with labs of cutting-edge molecular biology, muti-omics and imaging expertise in Edinburgh and across the UKDRI. The candidate will be exposed to an interdisciplinary environment with strong commitment of supporting early career researchers from the PI, the University, and the UKDRI. The initial appointment can be for 2 years, with the possibility of extension for 5 years. For inquiries, please send your CV and a brief personal statement describing your interest to Dr. Jian Gan at Jian.Gan@ed.ac.uk. A formal job vacancy link from the University of Edinburgh HR is attached here.

Further Information

https://elxw.fa.em3.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1001/job/4678

Contact Details

Dr. Jian Gan

Jian.Gan@ed.ac.uk.

UK Dementia Research Institute at the University of Edinburgh
Chancellor's Building
49 Little France Crescent
Edinburgh, EH16 4SB