- Vacancy Reference Number
- 22000000FZ
- Closing Date
- 17 Apr 2022
- Salary
- NIH scale
- Address
- 920 Madison Ave, Memphis, TN, USA, 38163
- Duration
- Aprox. 4 years.
This position is for a postdoctoral scholar for the Dept. of Genetics, Genomics & Informatics.
The department is looking for a postdoctoral scholar with experience in mitochondrial biology who will be part of a large project on the complex genetic and environmental interactions which influence longevity and cognitive aging. In Dr. Ashbrook’s group, the postdoc will be at the forefront of a newly funded R01 project, with opportunities to learn techniques in systems genetics, bioinformatics and in vivo biology.
This project is part of a long-term, multi-institution, collaboration using the BXD family of mice, and the AD-BXD Alzheimer’s disease model. The department is building upon a deep dataset including thousands of phenotypes stored in our GeneNetwork.org webservice. Current work in the lab is carrying out deep behavioral phenotyping. Previous work in the lab has identified a link between mitochondrial DNA copy number (mtDNAcn) and longevity, and part of this new project will be to elucidate the pathway by which this association takes place. The department has also found genetic background mediated differences in the effects of the 5XFAD Alzheimer’s disease model on behavioral and mitochondrial phenotypes. The ultimate goal of this postdoctoral position is to understand how genetic background, 5XFAD genotype, and environment mediate mtDNAcn, and the pathway by which this leads to differences in cognitive aging and longevity.
The successful applicant will be primarily within Dr. David Ashbrook’s lab in the Department of Genetics, Genomics and Informatics, but will also have opportunities to work with Dr. Aman Bajwa in the Department of Surgery (an expert in the role of mitochondria in liver injury), and Dr. Stephen Alway, Dean of the College of Health Professions (an expert in the role of mitochondria in aging muscle).
This position is funded by an NIH NIA R01 until December 2026.
Preliminary and informal inquiries are welcomed by email to Dr. Ashbrook
Qualifications
PhD in molecular biology, cellular biology, biochemistry, genetics, or similar field
Experience in mitochondrial biology
Expertise in molecular biological techniques such as quantitative RT-PCR
Experience of, or willingness to learn, bioinformatics and/or in vivo techniques
Good communication skills, both verbal and written
Curiosity, a critical research attitude, and an interdisciplinary mindset
Applicants should have a demonstrated commitment to and knowledge of equal employment opportunity and affirmative action.
The University of Tennessee Health Science Center is the flagship statewide, public, academic health institution in Tennessee. Founded in 1911, the mission of the University of Tennessee Health Science is to improve the health and well-being of Tennesseans and the global community by fostering integrated, collaborative, and inclusive education, research, scientific discovery, clinical care, and public service. Employing more than 4,600 people on its faculty, staff, and not-for-profit corporation faculty practice groups, and with more than 3,200 students across the state, UTHSC contributes $4 billion to the economy of Tennessee.
Part of the University of Tennessee System, the Health Science Center is headquartered in Memphis and includes all six of UT’s doctoral-degree-granting health science colleges -- Medicine, Dentistry, Pharmacy, Nursing, Graduate Health Sciences, and Health Professions. UTHSC spans the state with its four major, regional clinical health science locations in Memphis, Knoxville, Chattanooga, and Nashville, as well as more than 100 clinical education sites across Tennessee. UTHSC is the largest educator of health care professionals in the state and operates the state’s largest residency and fellowship advanced training programs.
Located in West Tennessee on the banks of the Mississippi River, Memphis is the second-largest city in the state and among the largest cities in the Southeast. The Greater Memphis metropolitan area has more than 1.3 million residents, and the city ranks among those with the lowest cost of living in the country. It is home to a vibrant restaurant scene, a revitalized Downtown, the Midtown Arts District, many scenic neighborhoods, an active medical district, and a burgeoning airport in the midst of a $214 million modernization.
Memphis boasts attractions, including Elvis Presley’s Graceland, the Memphis Grizzlies, historic Beale Street, the National Civil Rights Museum, the second-largest urban county park in the United States, and the Memphis in May World Championship Barbecue Cooking Contest.
Job Postdoctoral Fellows
Primary Location US-Tennessee-Memphis
Organization Genetics, Genomics & Informatics
Schedule Full-time
Campus/Institute Memphis
Job Posting Feb 22, 2022, 10:43:26 AM
Further Information
https://ut.taleo.net/careersection/ut_system/jobdetail.ftl?job=22000000FZ&tz=GMT-06%3A00&tzname=America%2FChicago
Contact Details
dashbrook@UTHSC.edu
