Research Assistant in Basic & Clinical Neuroscience Department (KCL)

Vacancy Reference Number
046847
Closing Date
8 Jun 2022
Salary
£33,114 per annum, including London Weighting Allowance
Address
Denmark Hill Campus, King's College London
Duration
Fixed-term contract to the 31st May 2023 with the possibility of a further extension.

About the job

Dementia is the greatest health challenge of our century.

Researchers at the UK Dementia Research Institute at King's College London are using innovative approaches to explore the biological mechanisms involved in neurodegenerative diseases. Their goal is to defeat dementia by uncovering vital new knowledge that will lead to the design of smarter diagnostics and effective treatments. The team aims to understand the fundamental biological processes involved in dementia at a molecular level - and to use that knowledge to design new ways to diagnose and treat disease more precisely.

Dr Sarah Mizielinska is seeking to appoint an organised and enthusiastic research assistant to develop a novel drug screening system in collaboration with a pharmaceutical company partner. Dr Sarah Mizielinska’s group research nucleocytoplasmic transport dysfunction related to RNA-binding protein proteinopathies, sharing common focus on the two neurodegenerative diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). This position will involve significant work in molecular biology, cell culture and microscopy.

You will join a research group based within the UK Dementia Research Institute (DRI) centre that is embedded within the Department of Basic and Clinical Neuroscience at King’s College London (www.kcl.ac.uk/ioppn/depts/bcn/dri/lab-groups) within the Maurice Wohl Clinical Neuroscience Institute on the Denmark Hill campus. The DRI is a national consortium focused on cutting-edge dementia research funded by the Medical Research Council, Alzheimer’s Society and Alzheimer’s Research UK (www.ukdri.co.uk).   

This post will be offered on an a fixed-term contract to the 31st May 2023 with the possibility of a further extension. 

This is a full-time post - 100% full time equivalent

 

Key responsibilities

  • Molecular biology, cell culture and microscopy techniques associated with the project
  • Maintenance of cell and stem cell cultures
  • Analysis, presentation, and communication of research findings
  • Maintaining accurate laboratory records
  • Manage the ordering of laboratory supplies
  • Undertake any other reasonable duties requested by Dr Mizielinska
  • May require flexibility for occasional weekend work (feeding stem cell cultures)

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

 

Essential criteria

  • BSc. In Cell Biology, Biochemistry, Neuroscience or related biological programme
  • Solid foundation knowledge in molecular and cellular biology
  • Experience in cell culture
  • Well-developed organisational and communication skills
  • Computer literate, able to use MS Word, Excel, PowerPoint and willing to learn new software

Desirable criteria

  • MSc. In Cell Biology, Biochemistry, Neuroscience, or related field
  • Understanding genetics and methods of genetic engineering (CRISPR etc.)
  • Experience in microscopy
  • Experience in induced pluripotent stem cell culture and differentiation
  • Understanding and or/experience in CRISPR gene editing
  • Managing multiple tasks concurrently

 

Contact details: Sarah Mizielinska, Sarah.mizielinska@kcl.ac.uk