New expert-led consensus to shape the future of MND drug discovery and development research
6th December 2023
Dementia is the biggest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
The UK DRI at Cardiff is one of 7 UK centers bringing together world-leading scientists to deliver a step-change in the scientific understanding of dementia, generating new targets for drug development, reinvigorating the therapeutic pipeline and helping to transform care.
Applications are invited for a Research Associate position in Neuroinflammation/ Complement Biology in the UK DRI at Cardiff University School of Medicine, based in the Hadyn Ellis Building.
This post will join an ongoing programme of research that explores the roles of neuroinflammation in dementias. The work focusses on roles of the complement system, a known driver of neuroinflammation and neurodegeneration, and spans genetics, in vitro modelling, in vivo modelling and human studies to address three key questions: 1. When, where and why is complement dysregulated in the brain? 2. Does complement dysregulation drive neurodegeneration at different stages of disease? 3. Can inhibiting complement in the brain reduce disease? The ultimate aim of the work is to identify therapeutic strategies to modulate complement dysregulation in dementias.
Job Description
Main function
To conduct research within the area of dementias and contribute to the overall research performance of the School and University, carrying out research leading to the publishing of work in high-quality journals. To pursue excellence in research and to inspire others to do the same.
Main Duties and Responsibilities
Research
Other
Qualifications and Education
1. Postgraduate degree at PhD level (or nearing completion / submission) in a related subject area or experience in immunology, neuroimmunology and/or dementia models.
Knowledge, Skills and Experience
2. An established expertise and proven portfolio of research and/or relevant industrial experience within the following research fields:
i. Immunology and Inflammation biology
ii. Neuroscience and dementia research
3. Knowledge of current status of research in neuroimmunology and neurodegeneration
4. Proven ability to publish in national/international journals and/or present at relevant conferences
5. Knowledge and understanding of competitive research funding and process of developing applications to funding bodies
Communication and Team Working
6. Proven ability in effective and persuasive communication
7. Ability to supervise the work of others, to work as part of a team and focus team efforts, and to motivate individuals
Other
8. Proven capacity for creativity, innovation and team-working within the workplace
Desirable Criteria
9. Relevant professional qualification(s)- PhD in relevant subject area
10. Evidence of collaborations with industry.
11. Proven ability to adapt to the changing requirements of the Higher Education community.
12. Evidence of ability to participate in and develop both internal and external networks and utilise them to enhance the research activities of the School
Candidates with Postgraduate degree at PhD level (or nearing completion / submission) in a related subject area or experience in immunology, neuroimmunology and/or dementia models are encouraged to apply.
To apply visit here
Informal inquiries should be made to Prof. B. Paul Morgan (morganbp@cardiff.ac.uk) or Dr Wiola Zelek (zelekw@cardiff.ac.uk).