New expert-led consensus to shape the future of MND drug discovery and development research
6th December 2023
Dementia is the biggest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
The UK DRI at Cardiff is one of 7 UK centers bringing together world-leading scientists to deliver a step-change in the scientific understanding of dementia, generating new targets for drug development, reinvigorating the therapeutic pipeline and helping to transform care.
Applications are invited for a Research Technician position in Neuroinflammation/ Complement Biology in the UK DRI at Cardiff University School of Medicine, based at the Hadyn Ellis Building.
This post will join a new programme of research supported by LifeArc that explores the role of neuroinflammation in Alzheimer’s disease (AD). The work focuses on the roles of the complement system, a known driver of neuroinflammation and neurodegeneration, and the development and testing of novel brain-penetrant complement-blocking drugs in vitro and in vivo for their ability to inhibit the complement system, their penetrance into the brain, and their impact on disease pathology and disease progression. The ultimate aim of the work is to develop brain-penetrant therapeutic strategies to modulate complement dysregulation in AD that are applicable to human trials.
Candidates with experience in supporting similar laboratory research are encouraged to apply.
Support the University within ongoing programmes of work in dementia, carrying out supporting work, providing advice, guidance and support, and leading projects within this area
Key Duties
General Duties
Qualifications and Education
1. Degree/NVQ 4 or equivalent Professional membership/experience
Knowledge, Skills and Experience
2. Substantial experience of working within specialist discipline
3. Able to demonstrate professional knowledge within specialist discipline to give advice and guidance to internal and external customers
4. Ability to set up standard office systems and procedures and make improvements as appropriate
Customer Service, Communication and Team Working
5. Ability to communicate conceptually detailed and complex information effectively and professionally with a wide range of people
6. Evidence of ability to explore customers’ needs and adapt the service accordingly to ensure a quality service is delivered
Planning, Analysis and Problem solving
7. Evidence of ability to solve expansive problems using initiative and creativity; identifying and proposing practical solutions and resolving problems with range of potential outcomes
8. Evidence of demonstrable knowledge of key advances within specialist discipline
9. Evidence of ability to work unsupervised to deadlines, planning and setting priorities for own work and that of others and monitoring progress.
Other
10. A willingness to undertake further training and development
Desirable Criteria
11. Postgraduate/Professional qualification
12. Experience of working in a Higher Education or Pharma/Industrial environment
13. Fluency in Welsh, written and Oral
Additional Information
IMPORTANT: Evidencing Criteria
It is the School of Medicine's policy to use the person specification as a key tool for short-listing. Candidates should evidence that they meet ALL of the essential criteria as well as, where relevant, the desirable. As part of the application process you will be asked to provide this evidence via a supporting statement.
In order to apply visit here.
Informal inquiries should be made to Prof. B. Paul Morgan (morganbp@cardiff.ac.uk) or Dr. Wioleta Zelek (zelekw@cardiff.ac.uk).