Alzheimer's Society-funded PhD position available to study the role of ATF3 in tau-mediated neurodegeneration. We have previously identified an upregulation of the transcription factor ATF3 in mouse models of neurodegeneration. While ATF3 has been shown to have a protective role in motor neurons, little is known about its function within the brain. This studentship will use cell biological and biochemical approaches to investigate the effects of ATF3 expression in primary neurons at early stages of tauopathy. Understanding the mechanisms that underlie the neurodegeneration found in dementias is an important route to finding therapies for these diseases. The project is funded for 3 years and welcomes applicants from the UK and EU who have or expect to obtain at least an upper second class degree in Biological Sciences or allied subjects.
Due to funding restrictions this position is only open to UK/EU applicants
Applications will be considered in the order that they are received, and the position will be considered filled when a suitable candidate has been identified.
General enquiries should be made K.Deinhardt@soton.ac.uk. Any queries on the application process should be made to fels-pgr-apply@soton.ac.uk.
