Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, West Wing and Weatherall Institute of Molecular Medicine, Oxford
Grade 7: £32,236 - £39,609 p.a.
Please note that there are two positions available in this project. Should you wish to be considered for both, please ensure that you also submit an application for the following vacancy: 138962.
We are looking for talented, ambitious and dedicated scientists to work on a new project to understand the blood-brain-barrier in health and disease.
You will be part of the IM2PACT consortium, an important multi-centre European project led by Dr Zameel Cader. The aims of the project are to profile the molecular changes in the human blood-brain-barrier using bulk and single cell transcriptomics and proteomics. This will then inform the development of human induced pluripotent stem cell based disease models of neurovascular units.
Reporting to Dr Olaf Ansorge and Dr Imre Mager, you will be leading on molecular profiling of human brain cerebrovasculature. You will have strong experience of performing omics on tissue and or extensive experience with histopathology.
To be considered for this post, you must hold a relevant PhD/DPhil and have worked with tissue from humans or preclinical models for molecular profiling, (e.g. RNAseq) or histopathology. You should possess molecular biology skills including PCR, gRT-PCR, Western Blotting and Immunofluorescence. Research experience in neurological disorders and laser capture microdissection or microvessel enrichment would prove beneficial.
You are encouraged to contact Dr Zameel Cader (zameel.cader@ndcn.ox.ac.uk), to discuss the project further.
The post is full-time for a fixed-term until the 31 March 2022 in the first instance.
Only applications received before 12.00 midday on 4 March 2019 will be considered. Interviews will be held on the 14 March 2019.
For more information and to apply, click here
Dr Zameel Cader: zameel.cader@ndcn.ox.ac.uk
