Dementia is the biggest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
Rapid advances in DNA technologies and computational biology are enabling scientists to identify more and more of the subtle DNA variations that can influence a person’s risk of developing different neurodegenerative diseases. Researchers at the UK DRI at Cardiff interrogate the host of genetic variations linked with neurodegenerative diseases to make new discoveries about disease processes. They use experimental model systems along with a variety of cutting-edge experimental methods and equipment to dissect the biology of many of these genes. Building on the team’s international reputation for complex data analyses, they develop and apply advanced computational approaches that enable them to make sense of huge datasets generated by complex experiments.
Applications are invited for a Research Associate position in Neuroinflammation/ Complement Biology in the UK DRI at Cardiff University School of Medicine, based at the Hadyn Ellis Building, and Henry Wellcome Building.
This post will join an ongoing programme of research that aims to develop novel drugs for targeting neuroinflammation in dementias. The work focusses on developing new drugs targeting the complement system, in collaboration with the Oxford Dementia Drugs Discovery Institute. The ultimate aim of the work is to identify new therapeutic strategies to modulate complement dysregulation in dementias.
Candidates with Postgraduate degree at PhD level (or nearing completion / submission) in a related subject area and experience in immunology, neuroimmunology and/or drug development or relevant industrial experience are encouraged to apply.
To apply visit here.
Informal inquiries should be made to Prof. B. Paul Morgan (morganbp@cardiff.ac.uk).
