Neurodegeneration and the 3Rs: Models, Mechanisms & Resources

External Event - 6th Dec 2016

The Scottish TSE Network (STN) will host their annual one-day international symposium at the Roslin Institute (Edinburgh, UK) on state of the art approaches to studying neurodegenerative diseases that are consistent with the 3R principles (replacement, refinement, reduction) of animals in research.

Topics will include cell-free protein misfolding assays, human stem cell-based approaches and transgenic C. elegans and Drosophila models, in addition to the opportunities offered by tissue banking and in silico analysis. 

  • Plenary lecture: Rick Morimoto (Northwestern University, USA) who has made major contributions to the fields of protein folding/misfolding, cellular stress, aging and disease.
  • Invited speakers: Surachi Supattapone (Dartmouth College, USA); Raymond Bujdoso and Maria Spillantini (University of Cambridge); Hugh Perry (University of Southampton); James Alibhai, Tom Freeman, Nora Hunter, Malcolm Macleod, Colin Smith (University of Edinburgh).

The programme has been put together with the involvement of the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NS3Rs). Sam Jackson will describe the Centre’s work and outline funding opportunities.

For further information and registration please visit

Early registration is advisable.

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