New research into how Alzheimer's Disease develops

21st Nov 2016

New research published in Science, has shown that by manipulating one brain protein could allow the prevention of Alzheimer's. 

The protein, called tau protein, normally functions as a stabiliser for the microtubles that transport materials around the cell. Previous studies have suggested problems with tau protein being linked to Alzheimer's. The protein can clump together in twisted tangles and could be releasing Alzheimer's-inducing toxic chemicals.

In the study, an enzyme called p38γ Kinase interfered with the accumulation of the protein called beta-amyloid, which is a suspected cause of Alzheimer's. The tangling of beta-amyloid appeared to cuase a domino effect that sets off the clumping of tau proteins.

The researchers discovered how hindering the beta-amyloid mutation using p38γ Kinase also stopped tau protein from tangling in the mice. 

It could be many more years until this research is transitioned into an affective treatment for humans, but more and more scientists are taking steps toward a cure. 

To read more about this new research, please visit Science

< Back to News