Lecturer

University of Liverpool

Contract type
Contract-4 year
Closing date
04 Dec 2025 12:00 AM
Location
University of Liverpool
Salary
£23,280

Exciting PhD Opportunity in Immuno-Oncology & Neuroscience

Are you ready to tackle one of the most pressing safety challenges in immuno-oncology? We are offering a DiMeN DTP iCASE MRC-funded PhD studentship in the Dickens Lab, in collaboration with AstraZeneca.

This multidisciplinary project is a scientifically rigorous, translational project at the nexus of neuroscience, immunology, and drug safety. You will investigate Immune Cell-Associated Neurotoxicity Syndrome (ICANS)- an acute, potentially severe neurologic toxicity that can occur after T-cell–based therapies by decoding how blood–brain barrier (BBB) integrity is compromised and how we can protect it.

Multidisciplinary team with internationally recognised expertise:
David Dickens (BBB biology, University of Liverpool)
Munir Pirmohamed (Drug safety and clinical pharmacology, University of Liverpool)
Mahnoush Bahjat (Immunotoxicology, AstraZeneca)
Albena Dinkova-Kostova (NRF2 biology, University of Dundee)
The team has a strong track record in PhD mentorship and in developing innovative models to evaluate immune safety risks.

For further information please see https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-towards-mitigating-severe-neurotoxicity-in-t-cell-immunotherapy/?p189163

All applications are made via the application form accessed on the DiMeN website at www.dimen.org.uk/ with the deadline for applications being the 4th of December 2005. This is a fully funded project for UK and Irish students only “Home Students”