Research Fellow (Edinburgh)
UK Dementia Research Institute
Dementia is the biggest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
The Edinburgh Centre of the UK Dementia Research Institute is a collaborative research environment, focusing on understanding how vascular cells, macroglia, microglia and neurons interact to maintain brain homeostasis in health, and drive pathological cascades in disease.
We are looking for a postdoctoral Research Fellow to join the Rajani Lab as part of the new national BHF-UK DRI Centre for Vascular Dementia Research.
The Opportunity:
The Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias. We use a range of innovative methodologies and models to understand oligodendrocyte changes in vascular disease, and the interaction of these with neuronal activity. In this project the Research Fellow will use advanced techniques to investigate and manipulate neuronal activity in rodent models of vascular dementia, with the aim of understanding how this affects white matter.
Your skills and attributes for success:
- A PhD (or close to completion) in neuroscience or other relevant discipline.
- Extensive experience with in vivo two-photon calcium imaging.
- Ability to work independently.
- Proactive and creative independent thinker.
- Ability to problem-solve and troubleshoot technical difficulties.