Research Technician in Neuroepigenomics (Imperial)
UK DRI
The UK DRI at Imperial brings together researchers from diverse backgrounds with fresh perspectives, drawing on the university’s unique strengths, resources and focus on science, engineering, medicine and business. The team recognises that the challenges of dementia demand new concepts, new approaches and a diverse range of new research tools and directions. Their holistic approach views the ageing brain in the context of the ageing body, not in isolation.
About the role
We are seeking to appoint a Research Technician in Neuroepigenomics in the group of Dr Alexi Nott (https://nottgroup.com/index.html). Dr Nott’s research focuses on understanding how the epigenome and chromatin architecture regulates cell type gene expression programs in the healthy brain and during aging and disease.
What you would be doing
Building on laboratory experience in neuroscience, you will:
- Characterise chromatin factors from microglia, vascular and other brain cell types in human models of neuroinflammation.
- Identify and develop suitable techniques, and apparatus, for the collection and analysis of nuclei from human brain tissue.
- Demonstrate an aptitude for an organised, methodical approach to your work
- Provide up-to-date technical expertise, advice and support for specialised methods appropriate to the research projects
What we are looking for
A good qualification in Molecular Biology, Neuroscience, or a relevant laboratory science or equivalent vocational qualification
- Experience of laboratory-based molecular biology and biochemistry research
- Experience of nuclei isolation from brain tissue
- Excellent communication skills and a willingness to learn and implement complex techniques